Iberoamerican Journal of Medicine
Iberoamerican Journal of Medicine
Original article

Evidence-Based Data Regarding the Use of Antibiotic-loaded Cement in Hip Arthroplasty. A bibliometric analysis of 50 years

Datos basados en la evidencia sobre el uso de cemento con antibióticos en la artroplastia de cadera. Análisis blbliométrico de 50 años

Sebastian Alejandro Arias Tamayo, María Paula Lugo Pinilla, Andres Granados Zarate, José Daniel Cuastumal Martínez, Juan Felipe Casabon Pastrana, Jesus David Tipon Mayorga, Paula Alejandra Bernal Rojas, Cesar Mauricio Arango Ospina, Edwin Alejandro Gallego Gonzalez, Michael Ortega Sierra

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Introduction: The use of antibiotic-loaded cement is an intraoperative tool that has demonstrated potential benefits in hip arthroplasty. However, the global landscape of research on this topic remains unknown. The objective of this study was to analyze the scientific growth, characteristics, and metrics of global and historical research on the use of antibiotic-loaded cement in hip arthroplasty.
Material and methods: A cross-sectional bibliometric study was conducted using Scopus as the data source.
Results: A total of 523 documents published between 1973 and 2023 were selected. 89.9% (n=470) of the production consisted of original articles, with 11.85% being multi-center. 84.1% of the authors have published a single article, followed by 10.3% who have published two articles. Research has predominantly focused on adults or the elderly, with an emphasis on outcome evaluation (notably reoperation), assessing various antibiotic agents, and frequently employing retrospective designs.
Conclusions: There has been a sustained increase in research on the use of antibiotic-loaded cement in hip arthroplasty over the last 50 years. The research trend has shifted towards the evaluation of adult or elderly patients, exploration of antimicrobial agents, techniques, and health outcomes, primarily using observational and retrospective designs. An emerging research-focus is the study of hip arthroplasty in rheumatoid arthritis patients.


Bone cements; Anti-bacterial agents; Hip replacement arthroplasty; Bibliometrics


Introducción: El uso de cemento cargado con antibiótico, es una herramienta intraoperatoria que ha demostrado potenciales beneficios en la artroplastia de cadera. Sin embargo, se desconoce el panorama global de la investigación sobre este tópico. El objetivo de este estudio fue analizar el crecimiento científico, características y métricas de la investigación global e histórica sobre el uso de cemento cargado con antibiótico en artroplastia de cadera.
Material y métodos: Estudio bibliométrico de corte transversal, que utilizó como fuente de datos la base Scopus.
Resultados: Se seleccionaron 523 documentos publicados entre 1973 y 2023. El 89,9% (n=470) de la producción consistió en artículos originales, siendo el 11,85% multicéntricos. El 84,1% de los autores han publicado un único artículo, seguido de un 10,3% que han publicado dos artículos. La investigación se ha centrado predominantemente en adultos o ancianos, con énfasis en la evaluación de resultados (especialmente la reoperación), evaluando diversos agentes antibióticos y empleando con frecuencia diseños retrospectivos.
Conclusiones: En los últimos 50 años se ha producido un aumento sostenido de la investigación sobre el uso de cemento cargado con antibióticos en la artroplastia de cadera. La tendencia de la investigación se ha desplazado hacia la evaluación de pacientes adultos o ancianos, la exploración de los agentes antimicrobianos, las técnicas y los resultados sanitarios, utilizando principalmente diseños observacionales y retrospectivos. Un nuevo foco de investigación es el estudio de la artroplastia de cadera en pacientes con artritis reumatoide.

Palabras clave

Cementos para huesos; Antibacterianos; Artroplastia de reemplazo de cadera; Bibliometría


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