Iberoamerican Journal of Medicine
https://iberoamjmed.com/article/doi/10.53986/ibjm.2024.0011
Iberoamerican Journal of Medicine
Editorial

Enthesitis and seronegative arthritis induced by Dupilumab: how relevant are these adverse events?

Entesitis y artritis seronegative inducida por Dupilumab: ¿qué tan relevantes son estos eventos adversos?

Angélica María Hurtado Moreno, Urpy Osorio, Jennety Tatiana Peña Forest, Michael Ortega Sierra

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References

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2.Sakamoto E, Katahira Y, Mizoguchi I, Watanabe A, Furusaka Y, Sekine A, et al. Chemical- and Drug-Induced Allergic, Inflammatory, and Autoimmune Diseases Via Haptenation. Biology (Basel). 2023;12(1):123. doi: 10.3390/biology12010123.
3.De Stefano L, Bobbio-Pallavicini F, Montecucco C, Bugatti S. Dupilumab-induced enthesoarthritis and refractory atopic dermatitis successfully treated with baricitinib. Rheumatology (Oxford). 2022;61(3):e64-e66. doi: 10.1093/rheumatology/keab771.
4.Bridgewood C, Wittmann M, Macleod T, Watad A, Newton D, Bhan K, et al. T Helper 2 IL-4/IL-13 Dual Blockade with Dupilumab Is Linked to Some Emergent T Helper 17‒Type Diseases, Including Seronegative Arthritis and Enthesitis/Enthesopathy, but Not to Humoral Autoimmune Diseases. J Invest Dermatol. 2022;142(10):2660-7. doi: 10.1016/j.jid.2022.03.013.
5.Bridgewood C, Sharif K, Freeston J, Saleem B, Russell T, Watad A, et al. Regulation of entheseal IL-23 expression by IL-4 and IL-13 as an explanation for arthropathy development under dupilumab therapy. Rheumatology (Oxford). 2021;60(5):2461-6. doi: 10.1093/rheumatology/keaa568.
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Submitted date:
01/16/2024

Reviewed date:
03/06/2024

Accepted date:
03/11/2024

Publication date:
03/11/2024

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