Iberoamerican Journal of Medicine
https://iberoamjmed.com/article/doi/10.53986/ibjm.2022.0026
Iberoamerican Journal of Medicine
Case Report

Takotsubo syndrome and impending thyroid storm: A case report and brief review of the literature

Síndrome de Takotsubo y tormenta tiroidea inminente: reporte de un caso y breve revisión de la literatura

Yilmar Alexander Meza-González, Natalia Alfonso-Arrieta, Víctor Florez-García

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Abstract

Stress cardiomyopathy also called Takotsubo cardiomyopathy is characterized by transient regional systolic dysfunction of the left ventricle with electrocardiographic changes and an increase in troponin levels imitating myocardial infarction, but in the absence of angiographic evidence of obstructive coronary artery disease. Although the exact causal process has not been determined, it has been mentioned in connection with thyroid diseases.
We describe a woman's case that experienced severe chest pain along with electrical and analytical abnormalities. Significant ventricular dysfunction was present, and the invasive coronary angiography revealed no lesions, which was compatible with stress cardiomyopathy. Impending thyroid storm due to Graves’ disease was observed as a trigger and it is imperative to identify and treat any clinical variables that could put patients at risk for Takotsubo syndrome or have an impact on the course of their treatment.

Keywords

Hyperthiroidism; Cardiomiopathy; Takotsubo syndrome; Graves’ disease; Thyroid diseases

Resumen

La miocardiopatía por estrés, también llamada miocardiopatía de Takotsubo, se caracteriza por una disfunción sistólica regional transitoria del ventrículo izquierdo con cambios electrocardiográficos y un aumento en los niveles de troponina que simulan un infarto de miocardio, pero en ausencia de evidencia angiográfica de enfermedad arterial coronaria obstructiva. Aunque no se ha determinado el proceso causal exacto, se ha mencionado en relación con las enfermedades de la tiroides.
Describimos el caso de una mujer que presentaba dolor torácico intenso junto con anomalías eléctricas y analíticas. Presentaba importante disfunción ventricular y la coronariografía invasiva no mostraba lesiones, lo que era compatible con miocardiopatía de estrés. La tormenta tiroidea inminente debido a la enfermedad de Graves se observó como desencadenante y es imperativo identificar y tratar cualquier variable clínica que pueda poner a los pacientes en riesgo de síndrome de Takotsubo o tener un impacto en el curso de su tratamiento.

Palabras clave

Hipertiroidismo; Cardiomiopatía; Síndrome de Takotsubo; Enfermedad de Graves; Enfermedades tiroideas

References

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Submitted date:
06/24/2022

Reviewed date:
07/03/2022

Accepted date:
07/10/2022

Publication date:
07/10/2022

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