Iberoamerican Journal of Medicine
https://iberoamjmed.com/article/doi/10.53986/ibjm.2021.0053
Iberoamerican Journal of Medicine
Original article

The impact and effectiveness of new coronavirus vaccine on disease outcome worldwide

El impacto y la eficacia de la nueva vacuna contra el coronavirus en el resultado de la enfermedad en todo el mundo

Tasneem A. Alkout, Abdulhamid M. Alkout

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Abstract

Introduction: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is spreading rapidly around the world caused serious respiratory disease leading to death, therefore vaccine is the effective way to control this pandemic. Scientists tried to produce safe and effective SARS-CoV-2 vaccines in record time and vaccination program started in December 2020. The aim of this study to determine the impact of SARS-CoV-2 vaccine on COVID-19 disease.
Materials and methods: The COVID-19 cases data of post-vaccination and pre-vaccination were collected from Worldmeter website, and the percentage of vaccinated people data obtained from Statistics and Research Coronavirus Vaccinations. The statistical analyses performed with SPSS software version 16.0.
Results: The results showed countries with higher percentage of full dose vaccinated people correlated strongly with decrease of death and the severity of the disease among their infected population. This study showed that different vaccine mechanism against SARS-CoV-2 virus of more than 23.5% of vaccination people with full dose vaccine is effective to decrease death and serious symptoms of COVID-19 disease and increasing the recovery rate.
Conclusions: Different mechanism type of full dose vaccine against SARS-CoV-2 is effective to decrease death and serious symptoms of COVID-19 disease with increasing recovery rate. It was difficult to assess the effect of single dose alone, therefore more studies are recommended to assess the effect of single dose vaccine with COVID-19 disease outcome and to determine if the vaccine will accelerate the period of recovery rate and reduce the infectious period time in each country.

Keywords

Full vaccine; Total vaccine; COVID-19; SARS-CoV-2; mRNA vaccine; Vector vaccine; Inactivated virus vaccine

Resumen

Introducción: El síndrome respiratorio agudo severo por coronavirus 2 (SARS-CoV-2) se está propagando rápidamente por todo el mundo provocando una enfermedad respiratoria grave que conduce a la muerte, por lo que la vacuna es la forma eficaz de controlar esta pandemia. Los científicos intentaron producir vacunas contra el SARS-CoV-2 seguras y efectivas en un tiempo récord y el programa de vacunación comenzó en diciembre de 2020. El objetivo de este estudio es determinar el impacto de la vacuna contra el SARS-CoV-2 en la enfermedad COVID-19.
Materiales y métodos: Los datos de casos de COVID-19 de posvacunación y prevacunación se recopilaron del sitio web de Worldmeter, y el porcentaje de datos de personas vacunadas obtenidos de Estadísticas e Investigación de Vacunas por Coronavirus. Los análisis estadísticos realizados con el software SPSS versión 16.0.
Resultados: Los resultados mostraron que los países con un mayor porcentaje de personas vacunadas con la dosis completa se correlacionaron fuertemente con la disminución de la muerte y la gravedad de la enfermedad entre su población infectada. Este estudio mostró que el mecanismo de vacunación diferente contra el virus SARS-CoV-2 de más del 23.5% de personas vacunadas con la vacuna de dosis completa es eficaz para disminuir la muerte y los síntomas graves de la enfermedad COVID-19 y aumentar la tasa de recuperación.
Conclusiones: Diferentes tipos de mecanismos de vacuna de dosis completa contra el SARS-CoV-2 son efectivos para disminuir la muerte y los síntomas graves de la enfermedad COVID-19 con una tasa de recuperación creciente. Fue difícil evaluar el efecto de la dosis única sola, por lo que se recomiendan más estudios evaluar el efecto de la vacuna de dosis única con el resultado de la enfermedad COVID-19 y determinar si la vacuna acelerará el período de recuperación y reducirá el período de infección en cada país.

Palabras clave

Vacuna completa; Vacuna total; COVID-19; SARS-CoV-2; Vacuna de ARNm; Vacuna de vector; Vacuna de virus inactivado

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Submitted date:
09/01/2021

Reviewed date:
09/26/2021

Accepted date:
10/19/2021

Publication date:
10/19/2021

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