Iberoamerican Journal of Medicine
https://iberoamjmed.com/article/doi/10.5281/zenodo.5055900
Iberoamerican Journal of Medicine
Original article

The Diagnostic Power of the Platelet Mass Index for Testicular Tumours: A Simple Blood Test

El poder diagnóstico del índice de masa plaquetaria para los tumores testiculares: un simple análisis de sangre

Reha Girgin, Önder Çınar, Ersan Bulut, Bülent Akduman, Gökhan Çeker

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Abstract

Introduction: The relationship between inflammation and cancer has long been the focus of researchers' interest. There are many inflammatory markers studied for this purpose in the literature. In this context, we focused on the effects of platelet counts and platelet mass index (PMI) as inflammatory markers in the diagnosis of low-volume localized testicular cancer.
Materials and methods: Thirty-eight patients with localized testicular cancer with a mean age of 30.84 ± 5.79 years and 38 patients with varicocele as a control group with a mean age of 32.8 ± 9.7 years were enrolled in the study. Number of platelets, mean platelet volume and value of PMI were calculated from peripheral blood samples obtained.
Results: Number of platelets and PMI values were statistically significantly higher in patients with testicular cancer compared with the control group (p<.05).
Conclusions: Both platelet counts and PMI values can be used as a simple test in the diagnosis of testicular cancer besides the well-known accurate serum tumor markers as AFP (alpha fetoprotein), hCG (human chorionic gonadotropin) and LDH (lactate dehydrogenase).

Keywords

PMI; Testicular tumours; Biomarkers

Resumen

Introducción: La relación entre la inflamación y el cáncer ha sido durante mucho tiempo el foco de interés de los investigadores. Hay muchos marcadores inflamatorios estudiados con este propósito en la literatura. En este contexto, nos centramos en los efectos del recuento de plaquetas y el índice de masa plaquetaria (PMI) como marcadores inflamatorios en el diagnóstico de cáncer testicular localizado de bajo volumen.
Materiales y métodos: Se incluyeron en el estudio 38 pacientes con cáncer testicular localizado con una edad media de 30,84 ± 5,79 años y 38 pacientes con varicocele como grupo control con una edad media de 32,8 ± 9,7 años. El número de plaquetas, el volumen medio de plaquetas y el valor de PMI se calcularon a partir de muestras de sangre periférica obtenidas.
Resultados: El número de plaquetas y los valores de PMI fueron estadísticamente significativamente más altos en los pacientes con cáncer testicular en comparación con el grupo de control (p <.05).
Conclusiones: Tanto el recuento de plaquetas como los valores de PMI se pueden utilizar como una prueba simple en el diagnóstico de cáncer testicular, además de los marcadores tumorales séricos precisos bien conocidos como AFP (alfa fetoproteína), hCG (gonadotropina coriónica humana) y LDH (lactato deshidrogenasa).

Palabras clave

PMI; Tumores testiculares; Biomarcadores

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Submitted date:
05/22/2021

Reviewed date:
06/22/2021

Accepted date:
07/01/2021

Publication date:
07/01/2021

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