Iberoamerican Journal of Medicine
https://iberoamjmed.com/article/doi/10.5281/zenodo.3965555
Iberoamerican Journal of Medicine
Case Report

Bullous systemic lupus erythematosus: exceptional and challenging presentation

Salem Bouomrani, Sihem Riahi, Marwa Ben Houchet

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Abstract

Vesiculobullous lesions can be developed by less than 5% of patients with systemic lupus erythematosus (SLE). Among these lesions, bullous systemic lupus erythematosus (BSLE) is one of the rarest and most challenging cutaneous presentations of the disease. Its frequency in the largest series of 5149 patients with cutaneous lupus was 0.19%, and the majority of cases are reported as sporadic observation or small series not exceeding ten cases.
We report the original observation of BSLE revealing SLE in 32-year-old Tunisian Woman.
This atypical presentation of cutaneous lupus deserves to be known by clinicians and discussed in front of any bullous dermatosis, particularly in young woman.

Keywords

Bullous systemic lupus erythematosus; Cutaneous lupus; Systemic lupus erythematosus; Skin

References

1. Aringer M, Schneider M. [Systemic lupus erythematosus]. Dtsch Med Wochenschr. 2016;141(8):537-43. doi: 10.1055/s-0041-110604.
2. Rúa-Figueroa Fernández de Larrinoa I. What is new in systemic lupus erythematosus. Reumatol Clin. 2015;11(1):27-32. doi: 10.1016/j.reuma.2014.09.004.
3. Das NK, Dutta RN, Sengupta SR. Skin lesions in lupus erythematosus: a marker of systemic involvement. Indian J Dermatol. 2011;56(5):537-40. doi: 10.4103/0019-5154.87150.
4. Grover C, Khurana A, Sharma S, Singal A. Bullous systemic lupus erythematosus. Indian J Dermatol. 2013;58(6):492. doi: 10.4103/0019-5154.119973.
5. Chanprapaph K, Sawatwarakul S, Vachiramon V. A 12-year retrospective review of bullous systemic lupus erythematosus in cutaneous and systemic lupus erythematosus patients. Lupus. 2017;26(12):1278-84. doi: 10.1177/0961203317699714.
6. Pons-Estel GJ, Quintana R, Alarcón GS, Sacnún M, Ugarte-Gil MF, Pons-Estel BA, et al. A 12-year retrospective review of bullous systemic lupus erythematosus in cutaneous and systemic lupus erythematosus patients. Lupus. 2018;27(10):1753-4. doi: 10.1177/0961203318776104.
7. Hall RP, Lawley TJ, Smith HR, Katz SI. Bullous eruption of systemic lupus erythematosus. Dramatic response to dapsone therapy. Ann Intern Med. 1982;97(2):165-70. doi: 10.7326/0003-4819-97-2-165.
8. de Risi-Pugliese T, Cohen Aubart F, Haroche J, Moguelet P, Grootenboer-Mignot S, Mathian A, et al. Clinical, histological, immunological presentations and outcomes of bullous systemic lupus erythematosus: 10 New cases and a literature review of 118 cases. Semin Arthritis Rheum. 2018;48(1):83-9. doi: 10.1016/j.semarthrit.2017.11.003.
9. Ranario JS, Smith JL. Bullous lesions in a patient with systemic lupus erythematosus. J Clin Aesthet Dermatol. 2014;7(9):44-9.
10. Padrão EMH, Teixeira LF, Maruta CW, Aoki V, Felipe da Silva AS, Kim EIM, et al. Bullous systemic lupus erythematosus - a case report. Autops Case Rep. 2019;9(1):e2018069. doi: 10.4322/acr.2018.069.
11. Camisa C. Vesiculobullous systemic lupus erythematosus. A report of four cases. J Am Acad Dermatol. 1988;18(1 Pt 1):93-100. doi: 10.1016/s0190-9622(88)70014-6.
12. Duan L, Chen L, Zhong S, Wang Y, Huang Y, He Y, et al. Treatment of Bullous Systemic Lupus Erythematosus. J Immunol Res. 2015;2015:167064. doi: 10.1155/2015/167064.
13. Lowe CD, Brahe CA, Green B, Lam TK, Meyerle JH. Bullous systemic lupus erythematosus successfully treated with rituximab. Cutis. 2019;103(6):E5-E7.


Submitted date:
07/09/2020

Reviewed date:
07/28/2020

Accepted date:
07/29/2020

Publication date:
07/29/2020

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