Iberoamerican Journal of Medicine
Iberoamerican Journal of Medicine
Case Report

A case report on the importance of imaging in the diagnosis of Lipofibromatous Hamartoma of the median nerve

Luis Adiel Medrano-Danes, Francisco Rafael Espinosa-Leal, Roberto Ceniceros-Marrufo, Edelmiro Pérez-Rodríguez, Jesús Dante Guerra-Leal

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This case report presents a lipofibromatous hamartoma of the median nerve in a 31-year-old man who presents local deformity and a sensory deficit in the nerve territory. The tumor was evaluated with magnetic resonance, computed tomography, and plain film radiography, studying the pathognomonic findings of this tumor. The patient did not want surgical treatment because of prior surgical sequelae. A prior surgical biopsy was reported as a peripheral nerve with normal axonal fascicles surrounded by abundant fibroadipose tissue. This tumor has a low incidence with less than 180 cases reported in the literature.


Lipofibromatous hamartoma; Median nerve;Carpal tunnel; Magnetic resonance; Macrodactyly


1. Al-Jabri T, Garg S, Mani GV. Lipofibromatous hamartoma of the median nerve. J Orthop Surg Res. 2010;5:71. doi: 10.1186/1749-799X-5-71.
2. Toms AP, Anastakis D, Bleakney RR, Marshall TJ. Lipofibromatous hamartoma of the upper extremity: a review of the radiologic findings for 15 patients. AJR Am J Roentgenol. 2006;186: 805-11. doi: 10.2214/AJR.04.1717.
3. Tahiri Y, Xu L, Kanevsky J, Luc M. Lipofibromatous hamartoma of the median nerve: a comprehensive review and systematic approach to evaluation, diagnosis, and treatment. J Hand Surg Am. 2013;38:2055-67. doi: 10.1016/j.jhsa.2013.03.022.
4. Nilsson J, Sandberg K, Søe Nielsen N, Dahlin LB. Magnetic resonance imaging of peripheral nerve tumours in the upper extremity. Scand J Plast Reconstr Surg Hand Surg. 2009;43:153-9. doi: 10.1080/02844310902734572.
5. Nardella D, Sohawon S, Carlier A. Lipofibromatous hamartoma of the median nerve. Three case reports. J Plast Reconstr Aesthet Surg. 2009;62 :e314-7. doi: 10.1016/j.bjps.2007.11.061.
6. Cavallaro MC, Taylor JA, Gorman JD, Haghighi P, Resnick D. Imaging findings in a patient with fibrolipomatous hamartoma of the median nerve. AJR Am J Roentgenol. 1993;161:837-8. doi: 10.2214/ajr.161.4.8372770.
7. Kara M, Ozcakar L, Ekiz T, Yalçın E, Tiftik T, Akyüz M. Fibrolipomatous hamartoma of the median nerve: comparison of magnetic resonance imaging and ultrasound. PM R 2013;5:805-6. doi: 10.1016/j.pmrj.2013.03.026.
8. Okechi H, Dimostheni A, Kerscher SR, Gugel I, Bevot A, Schaefer JF, et al. Fibrolipomatous hamartomas of the median nerve in infancy and early childhood-imaging hallmarks, symptomatology, and treatment. Eur J Pediatr. 2018; 177 :567-73. doi: 10.1007/s00431-018-3100-7.
9. Giuliano V, Outwater EK, Mitchell DG, Burke MA. Median nerve hamartoma: MR imaging using chemical shift techniques. Magn Reson Imaging. 1997;15:1091-4. doi: 10.1016/s0730-725x(97)00155-0.

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